Position SummaryWe are seeking a skilled and detail-oriented Bioanalytical Analyst to join our Large Molecule Assay team within Research and Breakthrough Innovation at Elanco. This laboratory-based position is focused on the execution of ligand-binding assays (LBAs) to quantify monoclonal antibodies and other protein therapeutics in biological matrices. The ideal candidate will have hands-on experience with immunoassay platforms and a strong desire to learn about the unique challenges associated with the bioanalysis of large molecules.
Key Responsibilities- Perform ligand-binding assays (e.g., ELISA, MSD, Gyros) for the quantification of monoclonal antibodies in various biological fluids.
- Perform fit-for-purpose bioanalytical methods according to internal SOPs and global regulatory guidelines, assessing assay performance characteristics such as accuracy, precision, selectivity, sensitivity, and stability.
- Analyze samples from preclinical and clinical studies to provide high-quality data to our project teams
- Manage critical reagent inventory (e.g., capture/detection antibodies, standards) to ensure long-term assay consistency and performance.
- Aid in troubleshooting and resolving technical issues with assays.
- Assist with laboratory maintenance functions such as buffer preparation and laboratory inventory management
- Meticulously document all experimental procedures and results in an electronic lab notebook (ELN).
- Work in a highly collaborative, cross-functional matrix environment, communicating effectively with team members at various levels.
Required Qualifications- B.S. in Immunology, Biochemistry, Biology, or a related scientific discipline.
Preferred Qualifications- Hands-on experience performing quantitative ligand binding assays using platforms such as a spectrophotometer, Meso Scale Discovery (MSD), Gyros, or Quanterix.
- Experience with performing immunogenicity (Anti-Drug Antibody, ADA) assays.
- Familiarity with cell-based neutralizing antibody (NAb) assays.
- Strong data analysis skills and experience with relevant software (e.g., SoftMax Pro, Benchling).
- Excellent problem-solving abilities and a high degree of scientific rigor.
Don’t meet every single requirement? Studies have shown underrepresented groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!
Elanco Benefits and Perks:
We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
- Multiple relocation packages
- Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
- 8-week parental leave
- 9 Employee Resource Groups
- Annual bonus offering
- Flexible work arrangements
- Up to 6% 401K matching
